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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
18.48
Human Site:
S296
Identified Species:
33.89
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S296
S
L
V
D
V
D
I
S
Q
R
G
L
T
S
P
Chimpanzee
Pan troglodytes
XP_512211
535
59559
S239
Y
P
L
E
G
S
R
S
Y
C
L
D
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
L106
C
P
F
R
K
P
R
L
T
R
T
Q
S
A
F
Dog
Lupus familis
XP_548159
411
45633
L156
L
D
D
I
S
G
T
L
P
T
S
V
L
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S294
S
L
V
D
V
D
I
S
Q
R
G
L
T
S
P
Rat
Rattus norvegicus
XP_001081372
564
60962
S279
S
L
V
D
V
D
I
S
Q
R
G
L
T
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
Y233
V
P
L
E
E
G
M
Y
P
L
E
G
S
R
S
Chicken
Gallus gallus
XP_423895
264
29931
V10
Y
R
V
R
C
E
T
V
S
L
V
D
V
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
L448
D
T
S
S
Q
P
G
L
T
R
A
Q
S
A
F
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
S279
S
L
L
D
V
D
I
S
R
R
G
A
N
T
P
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
S702
V
L
H
S
E
K
K
S
Q
F
T
L
N
L
K
Honey Bee
Apis mellifera
XP_397211
804
90105
S469
S
H
K
E
K
V
D
S
E
R
E
K
I
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
E287
T
E
M
E
E
D
C
E
E
V
E
Q
N
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
13.3
6.6
0
N.A.
100
100
N.A.
0
6.6
N.A.
6.6
66.6
26.6
20
N.A.
6.6
P-Site Similarity:
100
33.3
20
6.6
N.A.
100
100
N.A.
26.6
13.3
N.A.
20
86.6
26.6
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
8
0
16
8
% A
% Cys:
8
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
8
31
0
39
8
0
0
0
0
16
0
8
0
% D
% Glu:
0
8
0
31
24
8
0
8
16
0
24
0
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
16
% F
% Gly:
0
0
0
0
8
16
8
0
0
0
31
8
0
0
8
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
31
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
8
0
16
8
8
0
0
0
0
8
0
8
16
% K
% Leu:
8
39
24
0
0
0
0
24
0
16
8
31
8
8
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% N
% Pro:
0
24
0
0
0
16
0
0
16
0
0
0
0
0
31
% P
% Gln:
0
0
0
0
8
0
0
0
31
0
0
24
0
0
0
% Q
% Arg:
0
8
0
16
0
0
16
0
8
54
0
0
0
8
0
% R
% Ser:
39
0
8
16
8
8
0
54
8
0
8
0
31
31
16
% S
% Thr:
8
8
0
0
0
0
16
0
16
8
16
0
24
8
0
% T
% Val:
16
0
31
0
31
8
0
8
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _